Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, Salk researchers have discovered a new function of mitochondria: they set off molecular alarms when cells are exposed to stress or chemicals that can damage DNA, such as chemotherapy. The results, published online in Nature Metabolism on December 9, 2019, could… Continue reading Mitochondria, DNA and Chemotherapy-resistant Tumors
A new study analyzed 2 million birth records and 3,000 cancer registry records and found that children born to obese mothers were 57% more likely to develop cancer, independent of other factors. This finding offers a rare opportunity for childhood cancer prevention. Using Pennsylvania birth records, the researchers found a correlation between pre-pregnancy body-mass index… Continue reading Is Maternal Obesity Linked to Childhood Cancer?
How did humans get to be so much fatter than our closest primate relatives, despite sharing 99% of the same DNA? A new study suggests that part of the answer may have to do with an ancient molecular shift in how DNA is packaged inside fat cells, which curbed our body’s ability to turn ‘bad’… Continue reading How Did Humans Become the “Fat Apes?”
Major depression, obesity and chronic pain are all linked to the effects of one protein, called “FK506-binding protein 51,” or FKBP51. Until now, efforts to inhibit this target have been hampered by the difficulty of finding something specific enough to do the job and not affect similar proteins. Now a research group has developed a… Continue reading Could Depression, Obesity and Chronic Pain All Be Treated by Suppression of One Protein?
The elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long known that a weakened immune system is to blame but the exact mechanisms behind this lagging immunity have remained largely unknown. Now research led by investigators at Harvard Medical School suggests that weakened metabolism of… Continue reading Weakened T-cells Linked to Age-related Immunity Loss: Study
Managing your weight can be a challenge. Life gets in the way. Food choices get in the way. Working out, well, it doesn’t always work out, does it? Maybe you’ve found a way to eat right and exercise that fits your lifestyle and actually works for you. Maybe you’re well on your way to your… Continue reading Sleep Loss and Weight Gain